This 90-minute webinar was created for physicians, nurses, and other health professionals who treat and case manage patients with active TB. The webinar introduced the 2016 Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis. This training highlighted the guidelines development process, the key changes in recommendations, and discussed the evidence supporting the changes. The webinar was originally presented on November 4, 2016. This training was jointly sponsored by all 5 RTMCCs.